Coexistence of Chronic Lymphocytic Leukemia and Myeloproliferative Neoplasm
نویسندگان
چکیده
منابع مشابه
Coexistence of Chronic Lymphocytic Leukemia and Myeloproliferative Neoplasm
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the Western world. Host immune surveillance caused mainly by the disease itself is speculated to be responsible for high incidence of secondary neoplasms. However, the simultaneous occurrence of CLL and myeloproliferative disorder in the same patient is extremely rare. In the present report, a case of an 81-year-old man who...
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Analysis of the blood smear, bone marrow aspiration, and bone marrow biopsy revealed the predomination of small lymphocytes, but 22% of the cells were blasts negative with cytochemical staining (Figure 1). Flow cytometric analysis showed two distinct populations: 65% of cells were small to moderate in size and CD19+, CD45+, CD5+, and CD20+/-, while 30% of cells were large, CD34+, CD13+, HLA DR+...
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Chronic lymphocytic leukemia (CLL) is a malignancy of B CD5+cells and is the most common type of leukemia in adults. The disease is more common in men over 50 years in western countries. CLL is associated with defective apoptosis in B cells. CLL was traditionally regarded as a disease that occurs before naïve B cells meet the antigen in the lymph nodes. Laboratory diagnosis requires white blood...
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ژورنال
عنوان ژورنال: Case Reports in Oncological Medicine
سال: 2014
ISSN: 2090-6706,2090-6714
DOI: 10.1155/2014/512928